Ziya Kaya Selected Research

PR-957

1/2021	Mitigated viral myocarditis in A/J mice by the immunoproteasome inhibitor ONX 0914 depends on inhibition of systemic inflammatory responses in CoxsackievirusB3 infection.
1/2020	Heart-Specific Immune Responses in an Animal Model of Autoimmune-Related Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation.
1/2020	ONX 0914 Lacks Selectivity for the Cardiac Immunoproteasome in CoxsackievirusB3 Myocarditis of NMRI Mice and Promotes Virus-Mediated Tissue Damage.
1/2018	The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis.

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Ziya Kaya Research Topics

Disease

26	Inflammation (Inflammations) 01/2022 - 02/2002
23	Myocarditis (Carditis) 01/2022 - 02/2002
14	Heart Failure 06/2018 - 09/2005
12	Fibrosis (Cirrhosis) 01/2022 - 10/2006
9	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 05/2021 - 08/2002
6	Cardiomyopathies (Cardiomyopathy) 01/2020 - 01/2010
4	Infections 01/2021 - 01/2020
4	Pain (Aches) 05/2016 - 11/2007
4	Infarction (Infarctions) 03/2010 - 10/2006
3	Neoplasms (Cancer) 05/2021 - 02/2014
3	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 03/2006
3	Virus Diseases (Viral Diseases) 06/2018 - 08/2002
3	Heart Diseases (Heart Disease) 01/2016 - 11/2008
3	Myocardial Infarction 12/2011 - 08/2008
2	Sepsis (Septicemia) 12/2020 - 01/2018
2	Body Weight (Weight, Body) 01/2019 - 03/2011
2	Chronic Hepatitis C 06/2018 - 07/2017
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2016 - 02/2013
2	Necrosis 05/2016 - 12/2011
2	Hypoxia (Hypoxemia) 03/2012 - 06/2008
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2010 - 03/2010
2	Ischemia 03/2010 - 06/2008
2	Acute Coronary Syndrome 08/2008 - 10/2006
1	Out-of-Hospital Cardiac Arrest 11/2021
1	Pancreatitis 01/2021
1	COVID-19 12/2020
1	Communicable Diseases (Infectious Diseases) 12/2020
1	Right Ventricular Dysfunction 12/2020
1	Psoriatic Arthritis 01/2019
1	Skin Manifestations 01/2019
1	Weight Gain 01/2019
1	Metabolic Diseases (Metabolic Disease) 01/2019
1	Abscess 01/2019
1	Arthritis (Polyarthritis) 01/2019
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2019
1	Critical Illness (Critically Ill) 07/2017
1	Strabismus (Squint) 12/2016
1	Disease Progression 01/2015

Drug/Important Bio-Agent (IBA)

19	Troponin IIBA 01/2022 - 10/2006
10	AutoantibodiesIBA 01/2017 - 08/2002
9	CytokinesIBA 01/2020 - 08/2002
8	ChemokinesIBA 01/2020 - 10/2006
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2006
6	AntibodiesIBA 01/2019 - 08/2002
5	HMGB1 Protein (HMG1)IBA 01/2016 - 06/2008
5	Chemokine CCL5IBA 10/2011 - 10/2006
5	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 07/2011 - 11/2005
4	RNA (Ribonucleic Acid)IBA 05/2021 - 11/2010
4	PR-957IBA 01/2021 - 01/2018
4	Troponin T (Troponin T1)IBA 12/2020 - 10/2006
4	InterferonsIBA 06/2018 - 09/2005
4	Interleukin-10 (Interleukin 10)IBA 12/2012 - 02/2002
3	Peptides (Polypeptides)IBA 01/2020 - 11/2008
3	Interleukin-6 (Interleukin 6)IBA 01/2019 - 07/2011
3	Chemokine ReceptorsIBA 10/2011 - 10/2006
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2011 - 08/2002
3	TroponinIBA 01/2010 - 10/2006
2	Biomarkers (Surrogate Marker)IBA 11/2021 - 12/2020
2	Immune Checkpoint InhibitorsIBA 05/2021 - 01/2020
2	Tramadol (K315)FDA LinkGeneric 01/2021 - 06/2012
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021 - 01/2020
2	Interleukin-17 (Interleukin 17)IBA 01/2020 - 01/2019
2	Immunoglobulin G (IgG)IBA 01/2020 - 01/2009
2	Messenger RNA (mRNA)IBA 01/2019 - 12/2012
2	Antiviral Agents (Antivirals)IBA 06/2018 - 07/2017
2	AntigensIBA 12/2016 - 08/2002
2	Myosins (Myosin)IBA 11/2015 - 01/2015
2	Cholinergic Agents (Cholinergics)IBA 02/2013 - 07/2011
2	ImmunosorbentsIBA 08/2012 - 01/2011
2	EnzymesIBA 08/2012 - 01/2011
2	InterleukinsIBA 10/2011 - 07/2011
2	Staphylococcal Protein A (Protein A)IBA 01/2010 - 01/2009
2	Complement System Proteins (Complement)IBA 03/2006 - 08/2002
1	lactate dehydrogenase 1 (LDH1)IBA 01/2022
1	locked nucleic acidIBA 01/2022
1	Antisense OligonucleotidesIBA 01/2022
1	OligonucleotidesIBA 01/2022
1	Carrier Proteins (Binding Protein)IBA 05/2021
1	Protein Isoforms (Isoforms)IBA 01/2021
1	Analgesics (Analgesic Drugs)IBA 01/2021
1	exopolyphosphataseIBA 12/2020
1	PolyphosphatesIBA 12/2020
1	Brain Natriuretic Peptide (Natrecor)FDA Link 12/2020
1	Desmoplakins (Desmoplakin)IBA 01/2020
1	GadoliniumIBA 01/2020
1	AdiponectinIBA 01/2019
1	Pharmaceutical PreparationsIBA 01/2018
1	Polyvinyl Chloride (PVC)IBA 05/2016
1	Interleukin-8 (Interleukin 8)IBA 05/2016
1	Glycyrrhizic Acid (Glycyrrhizin)IBA 01/2016
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 02/2015
1	Cyclophilin AIBA 01/2015

Therapy/Procedure

9	Therapeutics 01/2022 - 01/2009
3	Heart Transplantation (Grafting, Heart) 12/2020 - 01/2015
2	Vagus Nerve Stimulation 02/2013 - 07/2011
2	Transplantation 01/2013 - 11/2008
2	Ligation 10/2011 - 10/2006
1	Analgesia 01/2021
1	Anesthesia 12/2016
1	Aromatherapy 05/2016